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Heineken International were founded in 1864 by Gerard Adriaan Heineken in Amsterdam.
In 1869 Heineken switched to the use of bottom-fermenting yeast. In 1873 the brewery's name changed to Heineken's Bierbrouwerij Maatschappij (HBM), and opened a second brewery in Rotterdam in 1874. In 1886 Dr. H. Elion, a pupil of the French chemist Louis Pasteur, developed the "Heineken A-yeast" in the Heineken laboratory. This yeast is still the key ingredient of Heineken beer.
As of 2015, Heineken owns over 165 breweries in more than 70 countries and employs approximately 76,000 people. Besides Heineken Lager Beer, it brews and sells more than 250 other international premium, regional, local and specialty beers.